API
IMPURITY
CHEMICAL NAME
STRUCTURE
2
Dobutamine Hydrochloride

EP Impurity D (10-dehydroxy-10-oxo-7epi-docetaxel)

1,7α-dihydroxy-9,10-dioxo-5s,20-epoxytax-11-ene-2α,4,13α- tetrayl 4-acetate 2-benzoate 13-[(2R,3S)3-[[(1,1-dimethylethoxy)carbonyl]amino]-2-hydroxy-3-phenylpropanoate] DocetaxelTrihydrateEp Impurity D
DOCETAXEL TRIHYDRATE

EP Impurity C (7-epi-docetaxel)

1,7α-10s-trihydroxy-9-oxo-5s,20-epoxytax-11-ene-2α,4,13α- triyl 4-acetate 2-benzoate 13-[(2R,3S)3-[[(1,1- dimethylethoxy)carbonyl]amino]-2-hydroxy-3- phenylpropanoate] DOCETAXELTRIHYDRATEEP Impurity C
Docetaxel Trihydrate

EP Impurity C (7-epi-docetaxel)

1,7α-10s-trihydroxy-9-oxo-5s,20-epoxytax-11-ene-2α,4,13α- triyl 4-acetate 2-benzoate 13-[(2R,3S)3-[[(1,1- dimethylethoxy)carbonyl]amino]-2-hydroxy-3- phenylpropanoate] DocetaxelTrihydrateEP Impurity C(7-epi-docetaxel)
Docetaxel Trihydrate

EP Impurity B (10-dehydroxy-10-oxodocetaxel)

1,7 β-dihydroxy-9,10-dioxo-5 β,20-epoxytax-11-ene-2 α,4,13 α-triyl4-acetate2-benzoate13-[(2R,3S)3-[[(1,1- dimethylethoxy)carbonyl]amino]-2-hydroxy-3-phenylpropanoate] DocetaxelTrihydrateEP Impurity B
Docetaxel Trihydrate

DOCETAXEL impurity

Benzenerropanoic acid, β-[[(1,1-dimethylethoxy) carbonyl]amino]-α-hedroxy(2Ar,4S,4as,6R,9S,11S,12as,12bs,)-12b-(acetyloxy)-12(benzoyloxy)-2a,3,4,4a,5,6,9,11,12,12a,12b-dpdecajudrp-6,11-dojudrpxy-4a,8,13,13-tetramethyl-5-oxo-4-[[2,2-dichloroethoxy)carbonyl]oxy]-7,11-methano-1H-cyclodeca[3,4]benz[1,2b]oxet-9-yl
Domperidone

EP Impurity C

cis-4-(5-chloro-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)-1-[3-(2-oxo-2,3-dihydro-1Hbenzimidazol-1-yl)propyl]piperidine 1-oxide DomperidoneEP Impurity C