API
IMPURITY
CHEMICAL NAME
STRUCTURE
2
Montelukast

EP Impurity C

2-(1-(((S)-1-(3-((E)-2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propylsulfinyl)methyl)cyclopropyl) acetic acid(Montelukast Sulfoxide impurity) Montelukast-EP-Impurity-C
Montelukast

Ep Impurity F

2-(1-((((S)-3-(2-acetylphenyl)-1-(3-((E)-2-(7-chloroquinolin-2-yl)vinyl)phenyl)propyl)sulfanyl)methyl)cyclopropyl)acetic acid Montelukast-Ep-Impurity-F
Montelukast

EP Impurity

2-(1-((((R) -1-(3-(2-(7-Chloroquinolin-2-yl)ethyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propyl)Sulfonyl)methyl)cyclopropyl)acetic acid Montelukast-EP-Impurity
Montelukast

P Impurity B

2-(1-(((S)-1-(3-((E)-2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-(prop-1-en-2-yl)phenyl)propylthio)methyl)cyclopropyl)acetic acid(Montelukast Styrene impurity) Montelukast-EP-Impurity-B
Montelukast

EP Impurity

1-[[[(IR)-1-[3-[(IE)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropane acetamide (Montelukast amide impurity) Montelukast-EP-Impurity
Montelukast

EP Impurity

2-[2-[3(S)-[3-[2-(7-Chloro-2-quinolinyl)-ethynyl][phenyl]-3-hydroxypropyl]phenyl]-2-propanol EP-Impurity-7-Chloro-2
MONTELUKAST EP IMPURITY-A

MONTELUKAST EP IMPURITY-A

1-[[[(1S)-1-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropaneacetic acid sodium salt MONTELUKAST EP IMPURITY-A
MONTELUKAST SULPHOXIDE (IMPURITY-C)

MONTELUKAST SULPHOXIDE (IMPURITY-C)

[1-[[[1-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-3-[2-(2-hydrox-ypropan-2-yl)phenyl]propyl]sulfinyl]methyl]cyclopropyl]acetic acid. ss3