API
IMPURITY
CHEMICAL NAME
STRUCTURE
2
Perindopril

EP Impurity A

(2S,3aS,7aS)-octahydro-1H-indole-2-carboxylic acid
Perindopril

EP Impurity B

(2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-carboxybutyl]amino]propanoyl]octahydro-1Hindole-2-carboxylic acid
Perindopril

EP Impurity E

(2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-[(1methylethoxy)carbonyl]butyl]amino] propanoyl]octahydro-1H-indole-2-carboxylic acid Perindopril_EP-Impurity-E
Perindopril

EP Impurity B

(2S,3aS,7aS)-1-[(2S)-2[[(1S)1carboxybutyl]amino]propanoyl]octahydro-1Hindole-2-carboxylic acid Perindopril_EP-Impurity-B
PERINDOPRIL ARGININE REFERENCE STANDARD

PERINDOPRIL ARGININE REFERENCE STANDARD

"(2S,3aS,7aS)-1-[(2S)-2-[[(2S)-1-(Ethoxy-1-oxopentan-2-yl]amio]propanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid,(2S)-2-amino-5-(diaminomethylideneamino)pentanoic acid. " aw7
PERINDOPRIL IMPURITY-A

PERINDOPRIL IMPURITY-A

"(2S,3aS,7aS)-Octahydro-1H-indole-2-carboxylic acid " aw8
PERINDOPRIL IMPURITY-B

PERINDOPRIL IMPURITY-B

"(2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-Carboxybutyl]amino]propanoyl]octahydro-1H-indole-2-carboxylic acid " aw9
PERINDOPRIL IMPURITY-E

PERINDOPRIL IMPURITY-E

"(2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-[(1-Methylethoxy)carbonyl]butyl]amino]propanoyl]octahydro-1H-indole-2-carboxylic acid. " aw0
PERINDOPRIL IMPURITY-F

PERINDOPRIL IMPURITY-F

"Ethyl (2S)-2-[(3S,5aS,9aS,10aS)-3-methyl-1,4-dioxodecahydropyrazino[1,2-a]indol-2(1H)-yl]pentanoate. " ae1
PERINDOPRIL IMPURITY-I

PERINDOPRIL IMPURITY-I

(2S,3aS,7aS)-1-[(2S)-2-[[(1R)-1-(ethoxycarbonyl)butyl]ami-no]propanoyl]octahydro-1H-indole-2-carboxylic acid;(2S,3aS,7aS)-1-((S)-2-(((R)-1-ethoxy-1-oxopentan-2-yl)amino)propanoyl)octahydro-1H-indole-2-carboxylic acid. ae2
PERINDOPRIL IMPURITY-K

PERINDOPRIL IMPURITY-K

"(3S, 5aS, 9aS, 10aS)-3-Methyldecahydropyrazino [1, 2-a] indole-1, 4-dione. " ae3
PERINDOPRIL IMPURITY-H

PERINDOPRIL IMPURITY-H

(2S,3aS,7aS)-1-[(2S)-2-[(5RS)-3-cyclohexyl-2(cyclohexylimino)-4-oxo-5-propylimidazolidin-1-yl]propanoyl]octahydro-1H-indole-2-carboxylic acid salt. ae4
PERINDOPRIL ARGININE REFERENCE STANDARD

PERINDOPRIL ARGININE REFERENCE STANDARD

(2S,3aS,7aS)-1-[(2S)-2-[[(2S)-1-(Ethoxy-1-oxopentan-2-yl]amio]propanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid,(2S)-2-amino-5-(diaminomethylideneamino)pentanoic acid. perindropril
PERINDOPRIL ARGININE REFERENCE STANDARD

PERINDOPRIL ARGININE REFERENCE STANDARD

"(2S,3aS,7aS)-1-[(2S)-2-[[(2S)-1-(Ethoxy-1-oxopentan-2-yl]amio]propanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid,(2S)-2-amino-5-(diaminomethylideneamino)pentanoic acid. " perindorpil