API
IMPURITY
CHEMICAL NAME
STRUCTURE
2
Sertraline Hydrochloride

EP Impurity A

(1RS,4SR)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4- tetrahydronaphthalen-1-amine Sertraline-Hydrochloride-EP-Impurity-A
Sertraline Hydrochloride

EP Impurity C

(1RS,4RS)-4-(4-chlorophenyl)-N-methyl-1,2,3,4- tetrahydronaphthalen-1-amine Sertraline-Hydrochloride-EP-Impurity-C
Sertraline Hydrochloride

EP Impurity B

(1RS,4RS)-N-methyl-4-phenyl-1,2,3,4- tetrahydronaphthalen-1-amine Sertraline-Hydrochloride-EP-Impurity-B
Sertraline Hydrochloride

EP Impurity E

(2R)-hydroxyphenylacetic acid ((R)-mandelic acid) Sertraline-Hydrochloride-EP-Impurity-E
Sertraline Hydrochloride

EP Impurity F

(4R)-4-(3,4-dichlorophenyl)-3,4-dihydronaphthalen-1(2H)-one Sertraline-Hydrochloride-EP-Impurity-F
Sertraline Hydrochloride

Sertraline Oxime Impurity

(+/-)-4-(3,4-Dichlorophenyl)-3,4-dihydro-1(2H)-napthalenone.oxime Sertraline-Hydrochloride-Sertraline-Oxime-Impurity
Sertraline Hydrochloride

EP Impurity G

(1R,4R)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine(sertraline enantiome) Sertraline-Hydrochloride-EP-Impurity-G